Click here to see all the TRIP Evidence Reviews.
Evidence-Based Reports
- Levetiracetam (Generalised epileptic seizures). Midlands Therapeutics Review and Advisory Committee, 2007
- Levetiracetam (Partial onset epileptic seizures). Midlands Therapeutics Review and Advisory Committee, 2007
- Epilepsy or a family history of epilepsy increases the risk of schizophrenia or schizophrenia-like psychosis. Evidence-Based Mental Health, 2006
- Improving epilepsy services and care. MeReC, 2004
Guidelines
- Use of serum prolactin in diagnosing epileptic seizures. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. 2005
- Epilepsy. PRODIGY, 2006
- The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. NICE, 2004
Systematic Reviews
- Corticosteroids including ACTH for childhood epilepsy other than epileptic spasms. Cochrane Database of Systematic Reviews, 2007
- A systematic review of the effectiveness and cost-effectiveness of neuroimaging assessments used to visualise the seizure focus in people with refractory epilepsy being considered for surgery. NCCHTA, 2006
- Therapeutic monitoring of antiepileptic drugs for epilepsy. Cochrane Database of Systematic Reviews, 2007
- Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults: a systematic review and economic evaluation. NCCHTA, 2005
- The clinical effectiveness and cost-effectiveness of newer drugs for children with epilepsy. A systematic review. NCCHTA, 2006
- Lamotrigine versus carbamazepine monotherapy for epilepsy. Cochrane Database of Systematic Reviews, 2005
- Zonisamide add-on for drug-resistant partial epilepsy. Cochrane Database of Systematic Reviews, 2005
- Psychological treatments for epilepsy. Cochrane Database of Systematic Reviews, 2005
- Acupuncture for epilepsy. Cochrane Database of Systematic Reviews, 2006
- Oxcarbazepine versus phenytoin monotherapy for epilepsy. Cochrane Database of Systematic Reviews, 2006
Recent articles in core journals
- Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology, 2007
- The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet, 2007
- The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. Lancet, 2007
- First seizure presentation: do multiple seizures within 24 hours predict recurrence? Neurology, 2006
- Treatment of the first tonic-clonic seizure does not affect long-term remission of epilepsy. Neurology, 2006
- Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial. BMJ, 2006
- Adult epilepsy. Lancet, 2006
- Epilepsy in children. Lancet, 2006
eTextbooks
- Ganfyd
- eMedicine, Seizures and Epilepsy: Overview and Classification
- Merck Manual. Seizure Disorders
- GP Notebook
Clinical queries
- Which SSRI would be least likely to increase a patients seizure threshold? Rotherham PCT Q&A Service, 2006
- Does a first presentation of multiple seizures make subsequent seizures more likely? NLH Q&A Service, 2006
- What is the best acute management for a patient presenting with a first epileptic convulsion? NLH Q&A Service, 2006
- For women aged 42 years with epilepsy, is there any evidence that having an intrauterine device inserted increases the risk of epileptic seizure? FFPRHC, 2006
Patient information
- Epilepsy - seizures explained. Better Health Channel
- BUPA Health Information
- NHS Direct Online
- eMedicine Consumer Health
